Devereaux PJ, Yang H, Yusuf S et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet 2008; 371: 1839-1847.
RHH Journal Club. June 28th, 2012. Dr Carol Holgate
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To evaluate the effect of metoprolol vs. placebo on the 30-day risk of postoperative cardiovascular events.