PAFC: the yellow snake of death?

Sandham JD, Hull RD, Brant RF et al.  A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. New England Journal of Medicine 2003; 348: 5-14.

RHH Journal Club. May 23th, 2013. Dr Kris Sivarajan

Full-text article (if available)

Does the use of a PA catheter improve in hospital mortality in surgical patients?

Read more…

APC: how not to Survive Sepsis?

Bernard GR, Vincent JL, Laterre PF et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. New England Journal of Medicine 2001; 344: 699-709.

RHH Journal Club. May 16th, 2013. Dr Matt Smith

Full-text article (if available)

Does administration of drotrecogin alfa activated (APC) reduce the rate of death in patients with severe sepsis and have an acceptable safety profile?

Read more…

Salt is better than sugar

Myburgh JA, Finfer S, Bellomo R et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. New England Journal of Medicine 2012; 367: 1901-1911.

RHH Journal Club. November 22nd, 2012. Dr Balaji Kasa

No free full-text available

To evaluate the safety and efficacy of 6% HES (130/0.4) in 0.9% saline as compared to 0.9% saline alone for fluid resuscitation in ICU.

Read more…

Cooling off time to make you feel (neurologically) better…

The Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002; 346: 549-556.

RHH Journal Club. March 14th, 2012. Dr Rishav Goyal

Full-text article (if available)

Does induced hypothermia following cardiac arrest result in an improved neurological outcome?

Read more…

Simple interventions with great benefits – why we should “Match Michigan”

Pronovost P, Needham D, Berenholtz S et al. An intervention to decrease catheter-related bloodstream infections in the ICU. New England Journal of Medicine 2006; 355: 2725-2732.

RHH Journal Club. March 7th, 2012. Dr Reshma Bonsale

Full-text article (if available)

Can a central venous catheter care bundle reduce catheter-associated infections?

Read more…